The Nuffield Foundation is a British charitable trust with a longstanding commitment to advancing social well-being through research, analysis, and development. Its Main Grants scheme, part of the Research, Development & Analysis Fund, supports projects that generate evidence to inform policy and practice in areas such as education, welfare, justice, and science. The Foundation prioritises work that is rigorous, independent, and has the potential to influence decision-makers and improve outcomes for society. This call is open to a range of applicants, typically including academic researchers, policy analysts, and practitioners based in the UK. While the Foundation does not prescribe a single methodological approach, it values projects that demonstrate methodological soundness, originality, and a clear pathway to impact. Grants are awarded at varying levels, and the Foundation expects to fund work that might not attract support from other sources due to its policy relevance or interdisciplinary nature. The curatorial vision behind the Main Grants is to foster a portfolio of projects that collectively address pressing social issues. The Foundation seeks to support work that is both intellectually ambitious and practically grounded, with the ultimate goal of contributing to a fairer, more inclusive society. Applicants are encouraged to consider how their project aligns with the Foundation’s strategic priorities and to articulate a compelling case for support.